Hitozuma bôkô: Mimodaeru chibusa (2001)

Ever since losing her pharmacist husband, Nariaki, in a traffic accident, Yuko had been emotionally unstable and was under the care of Takeo—a doctor at the hospital where her husband had worked—and his wife, Ayako. After taking a tranquilizer given to her by Takeo, Yuko lost consciousness and was sexually assaulted by him. The drug was, in fact, a novel sexual stimulant that Nariaki himself had developed, and a major conflict soon erupted over its manufacturing manual.